Jordan R. Dherbey

Ph.D. Student
Affiliated projects
Background

I first studied about lab technician work in biomedical laboratories (both research and routine) in a private school from 2010 to 2013, and then molecular biology at the Grenoble Alpes University from 2014 to 2015.  I studied with Prof. Dr. Patrice Morand the expression of a neuroinflammatory envelop protein of the Multiple Sclerosis Associated Retrovirus (MSRV) and its potential implication in multiple sclerosis (more information here). During this period, I also worked on the optimisation of an ELISA test, specific of MSRV-Env.

For my second year of MSc in 2016, I went to Toulouse, where I studied the 3D orientation of the bony labyrinth in living hominoids and fossils hominins with Prof. Dr. José Braga (Braga et al. 2017). Then I moved to Bordeaux in 2017, where I worked with Dr. Yann Heuzé on the quantification of cranial morphological variation in a sample of children affected with nonsyndromic coronal craniosynostosis. This study aimed to create a severity gradient for this congenital disease, based on morphological criteria and tried to isolate individuals or groups of individuals sharing particular morphological characteristics.

Between January and July 2018, I worked at the Department of Systematics and Evolution, under the supervision of Prof. Dr. Thierry Wirth (Natural History Museum, Paris) on bacterial population genomics (mostly on Mycobacterium tuberculosis).

Research interests

Molecular genetics, pathogens and human evolution, biological anthropology.

Current project

I’ve started my Ph.D. in January 2019, under the supervision of Dr. Frederic Bertels in the Microbial Molecular Evolution group, on the experimental evolution of coliphage ΦX174. ΦX174 is a small, tailless bacteriophage with a 5386 bases circular single-stranded DNA genome. I am currently studying the adaptation of this coliphage to infecting different populations of E. coli strain C, resistant to the ancestral ΦX174 infection.

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